Home - Products - Apoptosis - NF-κB - Anti-inflammatory agent 51

Anti-inflammatory agent 51

CAS No. 2911610-03-0

Anti-inflammatory agent 51( —— )

Catalog No. M36969 CAS No. 2911610-03-0

Anti-inflammatory agent 51 is an amide/sulfonamide derivative with anti-inflammatory and potentially anti-tumor activity and inhibition of NF-κB activation, which can be used to study acute lung injury and ulcerative colitis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 49 Get Quote
10MG 83 Get Quote
25MG 132 Get Quote
50MG 196 Get Quote
100MG 284 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Anti-inflammatory agent 51
  • Note
    Research use only, not for human use.
  • Brief Description
    Anti-inflammatory agent 51 is an amide/sulfonamide derivative with anti-inflammatory and potentially anti-tumor activity and inhibition of NF-κB activation, which can be used to study acute lung injury and ulcerative colitis.
  • Description
    Anti-inflammatory agent 51 (compound 11d) is an amide/sulfonamide derivative with anti-inflammatory activities. Anti-inflammatory agent 51 inhibits NF-κB activation, has the potential for acute lung injury and ulcerative colitis research.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    NF-κB
  • Recptor
    NF-κB
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2911610-03-0
  • Formula Weight
    498.51
  • Molecular Formula
    C22H22N6O6S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (250.75 mM; Ultrasonic )
  • SMILES
    O=[N+]([O-])C1=CC=C(N2CCN(CC2)C3=CC=C(S(=O)(NCC4=NC=CC=C4)=O)C=C3[N+]([O-])=O)C=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Pan Chen, et al. Design, synthesis, and bioactivity evaluation of novel amide/sulfonamide derivatives as potential anti-inflammatory agents against acute lung injury and ulcerative colitis. Eur J Med Chem. 2023 Aug 2;259:115706. ?
molnova catalog
related products
  • (R)-(-)-Ibuprofen

    An enantiomer of Ibuprofen that is generally not considered a COX inhibitor and is instead thought to be involved in pathways of lipid metabolism as it is incorporated into triglycerides along with fatty acids.

  • Ganoderic acid H

    Ganoderic acid H is a potent antitumour agent, it mediates its biological effects through the inhibition of transcription factors AP-1 and NF-κB, resulting in the suppression of secretion of uPA.

  • Isoliquiritin apiosi...

    Isoliquiritin apioside isolated from Glycyrrhizae radix rhizome significantly decreases PMA-induced increases in MMP9 activities and suppresses PMA-induced activation of MAPK and NF-κB.